Are: Alzheimers Disease Case Study
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| Alzheimers Disease Case Study | 1 day ago · “While this study’s findings require further confirmation, the link it has identified between a well-functioning lymphatic system in the brain and the ability to reduce amyloid-beta accumulation may be a significant step forward in pursuing this class of therapeutics.” Abnormal buildup of amyloid-beta is one hallmark of Alzheimer’s disease. 2 days ago · This fictional case study presents an elderly patient with mild Alzheimer’s Disease (AD) who has experienced his first fall. Initial findings included poor balance, decreased strength, forgetfulness, reduced physical fitness and slow gait. The interventions consisted of an exercise-focused treatment program with an emphasis on functional tasks and balance exercises. 2 days ago · University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease. |
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The UCLA study has found that a one-time injection of an experimental stem cell therapy can promote recovery by repairing brain damage and improving memory function in mice with conditions that replicate human strokes and dementia. The study has been published in Science Translational Medicine. Glial cells In the study, the researchers used a specialised type of glial cells which surround and support neurons in the central nervous system. Thomas Carmichael, senior author of the study and interim director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and his team evaluated the effects of the glial cell therapy by injecting it into the brains of mice with brain damage similar to that seen in humans in the early to middle stages of dementia. The therapy was developed in collaboration with Bill Lowry, a UCLA professor of molecular, cell and developmental biology.New Case Studies
The brain surface is rendered as a translucent layer to provide anatomical context for the streamline display. White matter connections and the brain surface are displayed using different colors across for the same subject.
The findings appear this week in GeroScience. Traumatic brain injuries, or TBIs, affect over 1. In gray matter — the part of the brain that contains neuron cell bodies and their short-range connections — the most extensive similarities were in areas involved in memory temporal lobes and decision-making orbitofrontal cortices. In white matter — which connects different brain regions and allows their neurons to communicate across longer distances — the researchers found comparable degeneration patterns in structures such as the fornix, corpus callosum and corona radiata.
Whereas the fornix is involved in memory function, the corpus callosum facilitates information exchange between brain hemispheres. The corona radiata is involved in limb movement, and its injury can lead to poorer coordination and balance. Chronic TBI effects on cognitive function may be particularly severe in older people, who are approximately three times more likely to sustain a TBI than other age groups.]
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